Burkholderia thailandensis E264 ATCC 700388, BTH_II0875 (bimA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0875
Name
bimA
Replicon chromosome II
Genomic location 1026584 - 1028185 (- strand)
Transposon Mutants 1 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_439072.1
GI 83716561
Entrez 3845515
GI 83716561
NCBI Locus Tag BTH_II0875
RefSeq YP_439072.1
UniProtKB Acc Q2T6X7
UniProtKB ID Q2T6X7_BURTA

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia intracellular motility A, BimA
Product Name Confidence: Class 2
Synonyms Hep_Hag family protein
Evidence for Translation
Charge (pH 7) 13.87
Kyte-Doolittle Hydrophobicity Value -0.605
Molecular Weight (kDa) 55292.4
Isoelectric Point (pI) 10.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0427
Category Burkholderia intracellular motility A
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 63 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019364 (221 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0875
Search term: bimA

Human Homologs

References

Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei.
Stevens MP, Stevens JM, Jeng RL, Taylor LA, Wood MW, Hawes P, Monaghan P, Welch MD, Galyov EE
Mol Microbiol 2005 Apr;56(1):40-53
PubMed ID: 15773977