Burkholderia thailandensis E264 ATCC 700388, BTH_II0844 (bipD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0844
NCBI Locus TagBTH_RS04385
Name
bipD
Synonym: ipaD
Replicon chromosome II
Genomic location 984941 - 985798 (+ strand)
Transposon Mutants 2 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_439041.1
GI 83716730
Entrez 3845333
GI 83716730
INSDC ABC34619.1
NCBI Locus Tag BTH_RS04385
NCBI Old Locus Tag BTH_II0844
RefSeq YP_439041.1
UniParc UPI000178DEA9
UniProtKB Acc Q2T708
UniProtKB ID BIPD_BURTA
UniRef100 UniRef100_Q2T708
UniRef50 UniRef50_Q2T708
UniRef90 UniRef90_Q2T708

Product

Feature Type CDS
Coding Frame 1
Product Name
BprD protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -8.03
Kyte-Doolittle Hydrophobicity Value -0.364
Molecular Weight (kDa) 31088.7
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2J9T TOXIN 11/16/06 BipD of Burkholderia Pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.7 X-RAY DIFFRACTION 91.9
2IZP TOXIN 07/25/06 BipD - an invasion protein associated with the type-III secretion system of Burkholderia pseudomallei. BURKHOLDERIA PSEUDOMALLEI 2.1 X-RAY DIFFRACTION 91.9
2IXR TOXIN 07/10/06 BipD of Burkholderia Pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.6 X-RAY DIFFRACTION 91.9
3NFT TRANSPORT PROTEIN 06/10/10 Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 1.51 X-RAY DIFFRACTION 91.9

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 10 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019830 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0844
Search term: bipD
Search term: BprD protein

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
The type III secretion system needle tip complex mediates host cell sensing and translocon insertion.
Veenendaal AK, Hodgkinson JL, Schwarzer L, Stabat D, Zenk SF, Blocker AJ
Mol Microbiol 2007 Mar;63(6):1719-30
PubMed ID: 17367391