Burkholderia thailandensis E264 ATCC 700388, BTH_II0841 (bipB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0841
NCBI Locus TagBTH_RS04370
Name
bipB
Synonym: ipaB
Replicon chromosome II
Genomic location 981244 - 983118 (+ strand)
Transposon Mutants 1 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_439038.1
GI 83717078
Entrez 3846120
GI 83717078
INSDC AIP28860.1
NCBI Locus Tag BTH_RS04370
NCBI Old Locus Tag BTH_II0841
RefSeq WP_011401047.1
UniParc UPI0000667652
UniProtKB Acc A0A096YWA6
UniProtKB ID A0A096YWA6_BURTA
UniRef100 UniRef100_Q2T711
UniRef50 UniRef50_Q2T711
UniRef90 UniRef90_Q2T711

Product

Feature Type CDS
Coding Frame 1
Product Name
BipB protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.12
Kyte-Doolittle Hydrophobicity Value -0.092
Molecular Weight (kDa) 65043.3
Isoelectric Point (pI) 5.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 15 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004333 (399 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0841
Search term: bipB
Search term: BipB protein

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
The type III secretion system needle tip complex mediates host cell sensing and translocon insertion.
Veenendaal AK, Hodgkinson JL, Schwarzer L, Stabat D, Zenk SF, Blocker AJ
Mol Microbiol 2007 Mar;63(6):1719-30
PubMed ID: 17367391