Burkholderia thailandensis E264 ATCC 700388, BTH_II0804 (btaI3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0804
NCBI Locus TagBTH_RS04185
Name
btaI3
Replicon chromosome II
Genomic location 942512 - 943318 (- strand)

Cross-References

RefSeq YP_439001.1
GI 83717744
Entrez 3845023
GI 83717744
NCBI Locus Tag BTH_RS04185
NCBI Old Locus Tag BTH_II0804
RefSeq YP_439001.1
UniProtKB Acc Q2T748
UniProtKB ID Q2T748_BURTA

Product

Feature Type CDS
Coding Frame 1
Product Name
BtaI3
Synonyms N-acyl homoserine lactone synthase
Evidence for Translation
Charge (pH 7) 10.85
Kyte-Doolittle Hydrophobicity Value -0.126
Molecular Weight (kDa) 28856.6
Isoelectric Point (pI) 9.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0433
Category Quorum sensing system
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 60 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003720 (981 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0804
Search term: btaI3
Search term: BtaI3

Human Homologs

References

Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation.
Chandler JR, Duerkop BA, Hinz A, West TE, Herman JP, Churchill ME, Skerrett SJ, Greenberg EP
J Bacteriol 2009 Oct;191(19):5901-9
PubMed ID: 19648250