Burkholderia thailandensis E264 ATCC 700388, BTH_II0695 (bceR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0695
NCBI Locus TagBTH_RS03620
Name
bceR
Replicon chromosome II
Genomic location 812467 - 815040 (+ strand)
Transposon Mutants 4 transposon mutants in E264 ATCC 700388
CommentMember of the bce-II gene cluster
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis.
CommentNote that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).

Cross-References

RefSeq YP_438894.1
GI 83716384
Entrez 3845143
GI 83716384
INSDC ABC34273.1
NCBI Locus Tag BTH_RS03620
NCBI Old Locus Tag BTH_II0695
RefSeq YP_438894.1
UniParc UPI00006673B3
UniProtKB Acc Q2T7F5
UniProtKB ID Q2T7F5_BURTA
UniRef100 UniRef100_Q2T7F5
UniRef50 UniRef50_A3P7L1
UniRef90 UniRef90_A3P7L1

Product

Feature Type CDS
Coding Frame 1
Product Name
group 1 family glycosyl transferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 18.88
Kyte-Doolittle Hydrophobicity Value -0.068
Molecular Weight (kDa) 94356.2
Isoelectric Point (pI) 9.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 542 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003106 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0695
Search term: bceR

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863