Burkholderia thailandensis E264 ATCC 700388, BTH_II0687 (metZ)

Gene Feature Overview

Strain	Burkholderia thailandensis E264 ATCC 700388 GCF_000012365.1|latest
Locus Tag	BTH_II0687
NCBI Locus Tag	BTH_RS03580
Name	metZ
Replicon	chromosome II
Genomic location	803558 - 804775 (+ strand)
Transposon Mutants	2 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq	YP_438886.1
GI	83718046
Entrez	3844935
GI	83718046
NCBI Locus Tag	BTH_RS03580
NCBI Old Locus Tag	BTH_II0687
RefSeq	YP_438886.1
UniProtKB Acc	Q2T7G3
UniProtKB ID	Q2T7G3_BURTA

Product

Feature Type	CDS
Coding Frame	1
Product Name	O-succinylhomoserine sulfhydrylase
Synonyms
Evidence for Translation
Charge (pH 7)	-3.18
Kyte-Doolittle Hydrophobicity Value	-0.052
Molecular Weight (kDa)	43961.5
Isoelectric Point (pI)	6.32

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 568 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003101 (648 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BTH_II0687 Search term: metZ Search term: O-succinylhomoserine sulfhydrylase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000359976 cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501] E-value: 7.5e-55 Percent Identity: 35.3

References