Burkholderia thailandensis E264 ATCC 700388, BTH_II0686 (purF)

Gene Feature Overview

Strain	Burkholderia thailandensis E264 ATCC 700388 GCF_000012365.1|latest
Locus Tag	BTH_II0686
NCBI Locus Tag	BTH_RS03575
Name	purF
Replicon	chromosome II
Genomic location	801800 - 803335 (+ strand)
Transposon Mutants	1 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq	YP_438885.1
GI	83716414
Entrez	3844998
GI	83716414
INSDC	AIP27698.1
NCBI Locus Tag	BTH_RS03575
NCBI Old Locus Tag	BTH_II0686
RefSeq	WP_009895861.1
UniParc	UPI00006673CF
UniProtKB Acc	Q2T7G4
UniProtKB ID	Q2T7G4_BURTA
UniRef100	UniRef100_Q2T7G4
UniRef50	UniRef50_P0AG16
UniRef90	UniRef90_A1UZ47

Product

Feature Type	CDS
Coding Frame	1
Product Name	amidophosphoribosyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-8.52
Kyte-Doolittle Hydrophobicity Value	-0.203
Molecular Weight (kDa)	56443.6
Isoelectric Point (pI)	5.66

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 649 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003100 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BTH_II0686 Search term: purF Search term: amidophosphoribosyltransferase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000264220 phosphoribosyl pyrophosphate amidotransferase [Source:HGNC Symbol;Acc:HGNC:9238] E-value: 7.7e-73 Percent Identity: 37.9

References