Burkholderia thailandensis E264 ATCC 700388, BTH_II0543 (bceB)

Gene Feature Overview

Strain	Burkholderia thailandensis E264 ATCC 700388 GCF_000012365.1|latest
Locus Tag	BTH_II0543
NCBI Locus Tag	BTH_RS02835
Name	bceB
Replicon	chromosome II
Genomic location	645087 - 646469 (+ strand)
Transposon Mutants	3 transposon mutants in E264 ATCC 700388
Comment	Member of the bce-I gene cluster

Cross-References

RefSeq	YP_438743.1
GI	83717008
Entrez	3846166
GI	83717008
INSDC	AIP27787.1
NCBI Locus Tag	BTH_RS02835
NCBI Old Locus Tag	BTH_II0543
RefSeq	WP_011400941.1
UniParc	UPI000066760E
UniProtKB Acc	Q2T7V6
UniProtKB ID	Q2T7V6_BURTA
UniRef100	UniRef100_Q2T7V6
UniRef50	UniRef50_G7HLK8
UniRef90	UniRef90_A3P856

Product

Feature Type	CDS
Coding Frame	1
Product Name	undecaprenyl-phosphate glycosyl-1-phosphate transferase BceB
Synonyms	hypothetical protein
Evidence for Translation
Charge (pH 7)	17.56
Kyte-Doolittle Hydrophobicity Value	0.209
Molecular Weight (kDa)	52019.7
Isoelectric Point (pI)	10.23

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 517 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG016842 (593 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BTH_II0543 Search term: bceB Search term: undecaprenyl-phosphate glycosyl-1-phosphate transferase BceB

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863

Functional and topological analysis of the Burkholderia cenocepacia priming glucosyltransferase BceB, involved in the biosynthesis of the cepacian exopolysaccharide. Videira PA, Garcia AP, Sá-Correia I J Bacteriol 2005 Jul;187(14):5013-8 PubMed ID: 15995219

Plant host and sugar alcohol induced exopolysaccharide biosynthesis in the Burkholderia cepacia complex. Bartholdson SJ, Brown AR, Mewburn BR, Clarke DJ, Fry SC, Campopiano DJ, Govan JRW Microbiology 2008 Aug;154(Pt 8):2513-2521 PubMed ID: 18667584