Burkholderia pseudomallei K96243, BPSS1840

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1840
Name
Replicon chromosome 2
Genomic location 2501901 - 2502935 (- strand)

Cross-References

RefSeq YP_111844.1
GI 53722859
Entrez 3096352
GI 53722859
INSDC CAH39316.1
NCBI Locus Tag BPSS1840
RefSeq YP_111844.1,GeneID
UniParc UPI000043BE4D
UniProtKB Acc Q63J78
UniProtKB ID Q63J78_BURPS
UniRef100 UniRef100_Q3JK19
UniRef50 UniRef50_Q3JK19
UniRef90 UniRef90_Q3JK19

Product

Feature Type CDS
Coding Frame 1
Product Name
N-acetylmuramoyl-L-alanine amidase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -1.11
Kyte-Doolittle Hydrophobicity Value -0.349
Molecular Weight (kDa) 37543.0
Isoelectric Point (pI) 6.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 232 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019105 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1840

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268