Burkholderia pseudomallei K96243, BPSS1835 (bceA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1835
Name
bceA
Replicon chromosome 2
Genomic location 2496042 - 2497502 (+ strand)
CommentMember of the bce-I gene cluster

Cross-References

RefSeq YP_111839.1
GI 53722854
Entrez 3095239
GI 53722854
INSDC CAH39311.1
NCBI Locus Tag BPSS1835
RefSeq YP_111839.1,GeneID
UniParc UPI000043BE48
UniProtKB Acc Q63J83
UniProtKB ID Q63J83_BURPS
UniRef100 UniRef100_A0A069BAV3
UniRef50 UniRef50_A9AL04
UniRef90 UniRef90_Q2T7V7

Product

Feature Type CDS
Coding Frame 1
Product Name
BceA
Product Name Confidence: Class 2
Synonyms LPS biosynthesis mannose-1-phosphate guanylyltransferase
Evidence for Translation
Charge (pH 7) -8.56
Kyte-Doolittle Hydrophobicity Value -0.177
Molecular Weight (kDa) 52969.4
Isoelectric Point (pI) 6.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 472 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003312 (1226 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1835
Search term: bceA
Search term: BceA

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Wopperer J, Eberl L, Sá-Correia I, Leitão JH
Biochem Biophys Res Commun 2007 Feb 2;353(1):200-6
PubMed ID: 17184737
Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Leitão JH
Appl Microbiol Biotechnol 2008 Oct;80(6):1015-22
PubMed ID: 18668237