Burkholderia pseudomallei K96243, BPSS1749 (gnd)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1749
Name
gnd
Replicon chromosome 2
Genomic location 2398403 - 2399818 (- strand)

Cross-References

RefSeq YP_111755.1
GI 53722770
Entrez 3097024
GI 53722770
INSDC CAH39224.1
NCBI Locus Tag BPSS1749
RefSeq YP_111755.1,GeneID
UniParc UPI000043BDF4
UniProtKB Acc Q63JG7
UniProtKB ID Q63JG7_BURPS
UniRef100 UniRef100_A0A069BH75
UniRef50 UniRef50_P96789
UniRef90 UniRef90_A8ENX2

Product

Feature Type CDS
Coding Frame 1
Product Name
6-phosphogluconate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -8.12
Kyte-Doolittle Hydrophobicity Value -0.039
Molecular Weight (kDa) 50715.1
Isoelectric Point (pI) 5.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 476 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003043 (649 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1749
Search term: gnd

Human Homologs

Ensembl 97, assembly GRCh38.p12
phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891]
E-value: 9.1e-137
Percent Identity: 52.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268