Burkholderia pseudomallei K96243, BPSS1715 (gltA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1715
Name
gltA
Replicon chromosome 2
Genomic location 2354425 - 2355726 (- strand)

Cross-References

RefSeq YP_111721.1
GI 53722736
Entrez 3096977
GI 53722736
INSDC CAH39189.1
NCBI Locus Tag BPSS1715
RefSeq YP_111721.1,GeneID
UniParc UPI000043BDD2
UniProtKB Acc Q63JK1
UniProtKB ID Q63JK1_BURPS
UniRef100 UniRef100_A0A069BH20
UniRef50 UniRef50_P18789
UniRef90 UniRef90_N0ANM3

Product

Feature Type CDS
Coding Frame 1
Product Name
type II citrate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -0.81
Kyte-Doolittle Hydrophobicity Value -0.182
Molecular Weight (kDa) 48532.3
Isoelectric Point (pI) 6.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4XGH TRANSFERASE 12/30/14 X-ray Crystal Structure of Citrate Synthase from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS E264 2.1 X-RAY DIFFRACTION 99.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 551 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003071 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1715
Search term: gltA

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268