Burkholderia pseudomallei K96243, BPSS1689 (bceM)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1689
Name	bceM
Replicon	chromosome 2
Genomic location	2323068 - 2324036 (+ strand)
Comment	Member of the bce-II gene cluster

Cross-References

RefSeq	YP_111694.1
GI	53722709
Entrez	3095577
GI	53722709
INSDC	CAH39162.1
NCBI Locus Tag	BPSS1689
RefSeq	YP_111694.1,GeneID
UniParc	UPI000043BDB7
UniProtKB Acc	Q63JM8
UniProtKB ID	Q63JM8_BURPS
UniRef100	UniRef100_A0A069BAE4
UniRef50	UniRef50_Q4K5C5
UniRef90	UniRef90_I1WUU6

Product

Feature Type	CDS
Coding Frame	1
Product Name	GDP-6-deoxy-D-lyxo-4-hexulose reductase BceM
Synonyms	UDP-glucose 4-epimerase
Evidence for Translation
Charge (pH 7)	4.10
Kyte-Doolittle Hydrophobicity Value	-0.055
Molecular Weight (kDa)	34885.5
Isoelectric Point (pI)	8.61

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 636 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000738 (646 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1689 Search term: bceM Search term: GDP-6-deoxy-D-lyxo-4-hexulose reductase BceM

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863