Burkholderia pseudomallei K96243, BPSS1685 (bceQ)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1685
Name	bceQ
Replicon	chromosome 2
Genomic location	2316694 - 2318160 (- strand)
Comment	Member of the bce-II gene cluster
Comment	Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis

Cross-References

RefSeq	YP_111690.1
GI	53722705
Entrez	3096487
GI	53722705
INSDC	CAH39158.1
NCBI Locus Tag	BPSS1685
RefSeq	YP_111690.1,GeneID
UniParc	UPI000043BDB3
UniProtKB Acc	Q63JN2
UniProtKB ID	Q63JN2_BURPS
UniRef100	UniRef100_A0A069BGY9
UniRef50	UniRef50_Q13YU9
UniRef90	UniRef90_Q2T7F6

Product

Feature Type	CDS
Coding Frame	1
Product Name	lipopolysaccharide biosynthesis related membrane protein Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	17.63
Kyte-Doolittle Hydrophobicity Value	0.871
Molecular Weight (kDa)	51986.4
Isoelectric Point (pI)	10.57

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 56 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003105 (651 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1685 Search term: bceQ Search term: lipopolysaccharide biosynthesis related membrane protein

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863