Burkholderia pseudomallei K96243, BPSS1613

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1613
Name
Replicon chromosome 2
Genomic location 2189128 - 2189379 (- strand)
CommentThis gene is part of the type III secretion system T3SS-2 locus found in B. pseudomallei. B. pseudomallei T3SS-1 and T3SS-2, but not T3SS-3 contribute to pathogenicity in Solanum lycopersicum (tomato) but not human monocytic cell line THP-1. (PMID:20109238).

Cross-References

RefSeq YP_111621.1
GI 53722636
Entrez 3096787
GI 53722636
INSDC CAH39088.1
NCBI Locus Tag BPSS1613
RefSeq YP_111621.1,GeneID
UniParc UPI000043BD70
UniProtKB Acc Q63JV1
UniProtKB ID Q63JV1_BURPS
UniRef100 UniRef100_A0A097XJG8
UniRef50 UniRef50_A3NLP6
UniRef90 UniRef90_A3NLP6

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion protein
Synonyms
Evidence for Translation
Charge (pH 7) -1.53
Kyte-Doolittle Hydrophobicity Value -0.007
Molecular Weight (kDa) 8649.6
Isoelectric Point (pI) 5.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019915 (426 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1613

References

Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model.
Warawa J, Woods DE
FEMS Microbiol Lett 2005 Jan 1;242(1):101-8
PubMed ID: 15621426
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152