Burkholderia pseudomallei K96243, BPSS1611 (bpsaB2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1611
Name
bpsaB2
Replicon chromosome 2
Genomic location 2188230 - 2188685 (- strand)
CommentThis gene is part of the type III secretion system T3SS-2 locus found in B. pseudomallei. B. pseudomallei T3SS-1 and T3SS-2, but not T3SS-3 contribute to pathogenicity in Solanum lycopersicum (tomato) but not human monocytic cell line THP-1. (PMID:20109238).

Cross-References

RefSeq YP_111619.1
GI 53722634
Entrez 3095885
GI 53722634
INSDC CAH39086.1
NCBI Locus Tag BPSS1611
RefSeq YP_111619.1,GeneID
UniParc UPI000043BD6E
UniProtKB Acc Q63JV3
UniProtKB ID Q63JV3_BURPS
UniRef100 UniRef100_A0A069BA66
UniRef50 UniRef50_Q3BYL6
UniRef90 UniRef90_A0A088X7Z6

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system chaperone protein BpsaB2 (T3SS-2)
Product Name Confidence: Class 2
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -16.32
Kyte-Doolittle Hydrophobicity Value 0.042
Molecular Weight (kDa) 17253.2
Isoelectric Point (pI) 3.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 7 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017469 (470 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1611
Search term: bpsaB2

References

Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model.
Warawa J, Woods DE
FEMS Microbiol Lett 2005 Jan 1;242(1):101-8
PubMed ID: 15621426
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152