Burkholderia pseudomallei K96243, BPSS1549 (bsaK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1549
Name
bsaK
Synonym: sctI
Replicon chromosome 2
Genomic location 2103329 - 2103631 (+ strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus.

Cross-References

RefSeq YP_111555.1
GI 53722570
Entrez 3095550
GI 53722570
INSDC CAH39022.1
NCBI Locus Tag BPSS1549
RefSeq YP_111555.1,GeneID
UniParc UPI000043BD2F
UniProtKB Acc Q63K17
UniProtKB ID Q63K17_BURPS
UniRef100 UniRef100_Q3JL04
UniRef50 UniRef50_Q3JL04
UniRef90 UniRef90_Q3JL04

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system inner rod/minor needle component BsaK (T3SS-3)
Product Name Confidence: Class 2
Synonyms Type III secretion system protein
Evidence for Translation
Charge (pH 7) -3.77
Kyte-Doolittle Hydrophobicity Value -0.090
Molecular Weight (kDa) 10678.9
Isoelectric Point (pI) 4.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 7 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019859 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1549
Search term: bsaK

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW(1), Gan YH.
Trends Microbiol. 2010 Dec;18(12):561-8.
PubMed ID: 20951592
Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages.
Bast A(1), Krause K(1), Schmidt IH(1), Pudla M(2), Brakopp S(1), Hopf V(1), Breitbach K(1), Steinmetz I(1).
PLoS Pathog. 2014 Mar 13;10(3):e1003986.
PubMed ID: 24626296
PubMed ID: 28664152