Burkholderia pseudomallei K96243, BPSS1546 (bsaN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1546
Name
bsaN
Replicon chromosome 2
Genomic location 2100565 - 2101323 (- strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus. The original start codon (GTG) was replaced with an ATG that was 117 bp upstream of it (PMID:25085508).

Cross-References

RefSeq YP_111552.1
GI 53722567
Entrez 3096570
GI 53722567
NCBI Locus Tag BPSS1546
RefSeq YP_111552.1,GeneID
UniProtKB Acc Q63K20
UniProtKB ID Q63K20_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
regulator of type III secretion system effector proteins BsaN (T3SS-3)
Product Name Confidence: Class 2
Synonyms AraC family transcriptional regulator
Evidence for Translation
Charge (pH 7) 14.08
Kyte-Doolittle Hydrophobicity Value -0.110
Molecular Weight (kDa) 27860.8
Isoelectric Point (pI) 10.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 143 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019853 (327 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1546
Search term: bsaN

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon.
Chen Y, Schröder I, French CT, Jaroszewicz A, Yee XJ, Teh BE, Toesca IJ, Miller JF, Gan YH
BMC Microbiol 2014 Aug 1;14:206
PubMed ID: 25085508
Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei.
Sun GW, Chen Y, Liu Y, Tan GY, Ong C, Tan P, Gan YH
Mol Microbiol 2010 May;76(3):677-89
PubMed ID: 20345664