Burkholderia pseudomallei K96243, BPSS1544 (bsaP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1544
Name
bsaP
Synonym: sctW
Replicon chromosome 2
Genomic location 2097586 - 2098692 (- strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus.

Cross-References

RefSeq YP_111550.1
GI 53722565
Entrez 3096728
GI 53722565
INSDC CAH39017.1
NCBI Locus Tag BPSS1544
RefSeq YP_111550.1,GeneID
UniParc UPI000043BD2A
UniProtKB Acc Q63K22
UniProtKB ID Q63K22_BURPS
UniRef100 UniRef100_A0A095S5E2
UniRef50 UniRef50_Q2T723
UniRef90 UniRef90_Q2T723

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system gatekeeper protein BsaP (T3SS-3)
Product Name Confidence: Class 2
Synonyms Type III secretion system protein
Evidence for Translation
Charge (pH 7) -5.34
Kyte-Doolittle Hydrophobicity Value -0.258
Molecular Weight (kDa) 39900.4
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 15 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019849 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1544
Search term: bsaP

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW(1), Gan YH.
Trends Microbiol. 2010 Dec;18(12):561-8.
PubMed ID: 20951592
PubMed ID: 28664152
Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268