Burkholderia pseudomallei K96243, BPSS1538 (bsaV)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1538
Name
bsaV
Synonym: sctQ
Replicon chromosome 2
Genomic location 2091071 - 2092042 (- strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus.

Cross-References

RefSeq YP_111544.1
GI 53722559
Entrez 3096529
GI 53722559
INSDC CAH39011.1
NCBI Locus Tag BPSS1538
RefSeq YP_111544.1,GeneID
UniParc UPI000043BD24
UniProtKB Acc Q63K28
UniProtKB ID Q63K28_BURPS
UniRef100 UniRef100_A0A069B9Z4
UniRef50 UniRef50_Q2T717
UniRef90 UniRef90_Q62B01

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system cystoplasmic ring protein BsaV (T3SS-3)
Product Name Confidence: Class 2
Synonyms surface presentation of antigens protein
Evidence for Translation
Charge (pH 7) -2.04
Kyte-Doolittle Hydrophobicity Value 0.046
Molecular Weight (kDa) 34745.5
Isoelectric Point (pI) 6.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 18 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019841 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1538
Search term: bsaV

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152