Burkholderia pseudomallei K96243, BPSS1517

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1517
Name
Replicon chromosome 2
Genomic location 2070325 - 2070768 (- strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus.

Cross-References

RefSeq YP_111523.1
GI 53722538
Entrez 3095899
GI 53722538
INSDC CAH38990.1
NCBI Locus Tag BPSS1517
RefSeq YP_111523.1,GeneID
UniParc UPI000043BD0F
UniProtKB Acc Q63K49
UniProtKB ID Q63K49_BURPS
UniRef100 UniRef100_A0A069BDY7
UniRef50 UniRef50_I1WUA5
UniRef90 UniRef90_I1WUA5

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type III secretion system chaperone protein (T3SS-3)
Product Name Confidence: Class 2
Synonyms putative chaperone
Evidence for Translation
Charge (pH 7) -5.44
Kyte-Doolittle Hydrophobicity Value -0.250
Molecular Weight (kDa) 16578.8
Isoelectric Point (pI) 4.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 3 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019817 (267 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1517

Human Homologs

References

A genome-wide screen identifies a Bordetella type III secretion effector and candidate effectors in other species.
Panina EM, Mattoo S, Griffith N, Kozak NA, Yuk MH, Miller JF
Mol Microbiol 2005 Oct;58(1):267-79
PubMed ID: 16164564
BopC is a type III secreted effector protein of Burkholderia pseudomallei.
Muangman S, Korbsrisate S, Muangsombut V, Srinon V, Adler NL, Schroeder GN, Frankel G, Galyov EE
FEMS Microbiol Lett 2011 Oct;323(1):75-82
PubMed ID: 22092682
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152