Burkholderia pseudomallei K96243, BPSS1466

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1466
Name
Replicon chromosome 2
Genomic location 1999417 - 2000928 (- strand)

Cross-References

RefSeq YP_111472.1
GI 53722487
Entrez 3096623
GI 53722487
INSDC CAH38937.1
NCBI Locus Tag BPSS1466
RefSeq YP_111472.1,GeneID
UniParc UPI000043BCDC
UniProtKB Acc Q63KA0
UniProtKB ID Q63KA0_BURPS
UniRef100 UniRef100_Q3JL99
UniRef50 UniRef50_Q9DBF1
UniRef90 UniRef90_Q3JL99

Product

Feature Type CDS
Coding Frame 1
Product Name
aldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -1.03
Kyte-Doolittle Hydrophobicity Value 0.050
Molecular Weight (kDa) 53791.1
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 595 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004128 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1466

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 7 family member A1 [Source:HGNC Symbol;Acc:HGNC:877]
E-value: 1.0e-125
Percent Identity: 48.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268