Burkholderia pseudomallei K96243, BPSS1390 (bpscC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1390
Name
bpscC
Synonym: sctC
Replicon chromosome 2
Genomic location 1903732 - 1905498 (- strand)
CommentThis gene is part of the type III secretion system T3SS-1 locus found in B. pseudomallei but not B. mallei or B. thailandensis. B. pseudomallei T3SS-1 and T3SS-2, but not T3SS-3 contribute to pathogenicity in Solanum lycopersicum (tomato) but not human monocytic cell line THP-1. (PMID:20109238).

Cross-References

RefSeq YP_111402.1
GI 53722417
Entrez 3095732
GI 53722417
INSDC CAH38865.1
NCBI Locus Tag BPSS1390
RefSeq YP_111402.1,GeneID
UniParc UPI000043BC9F
UniProtKB Acc Q63KH0
UniProtKB ID Q63KH0_BURPS
UniRef100 UniRef100_A0A095RMN9
UniRef50 UniRef50_Q93L02
UniRef90 UniRef90_Q93L02

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system outer membrane ring protein / secretin BpscC (T3SS-1)
Product Name Confidence: Class 2
Synonyms type III secretion system protein
Evidence for Translation
Charge (pH 7) -2.88
Kyte-Doolittle Hydrophobicity Value -0.032
Molecular Weight (kDa) 62643.5
Isoelectric Point (pI) 6.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 285 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG020866 (286 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1390
Search term: bpscC

References

PubMed ID: 20109238
PubMed ID: 28664152
PubMed ID: 21768285
PubMed ID: 10403415
PubMed ID: 11990489
PubMed ID: 15621426