Burkholderia pseudomallei K96243, BPSS0913

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0913
Name
Replicon chromosome 2
Genomic location 1207153 - 1208454 (+ strand)

Cross-References

RefSeq YP_110922.1
GI 53721937
Entrez 3096921
GI 53721937
INSDC CAH38375.1
NCBI Locus Tag BPSS0913
RefSeq YP_110922.1,GeneID
UniParc UPI000043BACC
UniProtKB Acc Q63LU9
UniProtKB ID Q63LU9_BURPS
UniRef100 UniRef100_A0A069B8P9
UniRef50 UniRef50_A0A085JAZ0
UniRef90 UniRef90_I6ACH0

Product

Feature Type CDS
Coding Frame 1
Product Name
methionine gamma-lyase
Synonyms
Evidence for Translation
Charge (pH 7) -3.51
Kyte-Doolittle Hydrophobicity Value -0.065
Molecular Weight (kDa) 46678.5
Isoelectric Point (pI) 6.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017026 (421 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0913

Human Homologs

Ensembl 97, assembly GRCh38.p12
cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]
E-value: 8.3e-52
Percent Identity: 34.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268