Burkholderia pseudomallei K96243, BPSS0485 (hhqE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0485
Name
hhqE
Replicon chromosome 2
Genomic location 657606 - 658496 (+ strand)

Cross-References

RefSeq YP_110507.1
GI 53721522
Entrez 3095907
GI 53721522
INSDC CAH37941.1
NCBI Locus Tag BPSS0485
RefSeq YP_110507.1,GeneID
UniParc UPI000043B931
UniProtKB Acc Q63N12
UniProtKB ID Q63N12_BURPS
UniRef100 UniRef100_A3P2Y3
UniRef50 UniRef50_Q2T3X4
UniRef90 UniRef90_Q2T3X4

Product

Feature Type CDS
Coding Frame 1
Product Name
HhqE
Synonyms
Evidence for Translation
Charge (pH 7) 1.69
Kyte-Doolittle Hydrophobicity Value -0.037
Molecular Weight (kDa) 32280.5
Isoelectric Point (pI) 7.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 27 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017409 (462 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0485
Search term: hhqE
Search term: HhqE

Human Homologs

References

Functional genetic analysis reveals a 2-Alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria.
Diggle SP, Lumjiaktase P, Dipilato F, Winzer K, Kunakorn M, Barrett DA, Chhabra SR, Cámara M, Williams P
Chem Biol 2006 Jul;13(7):701-10
PubMed ID: 16873018