Burkholderia pseudomallei K96243, BPSS0484 (hhqD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0484
Name
hhqD
Replicon chromosome 2
Genomic location 656593 - 657591 (+ strand)

Cross-References

RefSeq YP_110506.1
GI 53721521
Entrez 3095088
GI 53721521
INSDC CAH37940.1
NCBI Locus Tag BPSS0484
RefSeq YP_110506.1,GeneID
UniParc UPI000043B930
UniProtKB Acc Q63N13
UniProtKB ID Q63N13_BURPS
UniRef100 UniRef100_A0A069BE51
UniRef50 UniRef50_P20582
UniRef90 UniRef90_Q2T3X3

Product

Feature Type CDS
Coding Frame 1
Product Name
HhqD
Synonyms
Evidence for Translation
Charge (pH 7) -0.35
Kyte-Doolittle Hydrophobicity Value 0.013
Molecular Weight (kDa) 35997.9
Isoelectric Point (pI) 6.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 579 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017408 (463 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0484
Search term: hhqD
Search term: HhqD

Human Homologs

References

Functional genetic analysis reveals a 2-Alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria.
Diggle SP, Lumjiaktase P, Dipilato F, Winzer K, Kunakorn M, Barrett DA, Chhabra SR, Cámara M, Williams P
Chem Biol 2006 Jul;13(7):701-10
PubMed ID: 16873018
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268