Burkholderia pseudomallei K96243, BPSS0483 (hhqC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0483
Name
hhqC
Replicon chromosome 2
Genomic location 655497 - 656603 (+ strand)

Cross-References

RefSeq YP_110505.1
GI 53721520
Entrez 3095761
GI 53721520
INSDC CAH37939.1
NCBI Locus Tag BPSS0483
RefSeq YP_110505.1,GeneID
UniParc UPI000043B92F
UniProtKB Acc Q63N14
UniProtKB ID Q63N14_BURPS
UniRef100 UniRef100_I1WRA8
UniRef50 UniRef50_Q0B3G1
UniRef90 UniRef90_Q2T3X2

Product

Feature Type CDS
Coding Frame 1
Product Name
HhqC
Synonyms
Evidence for Translation
Charge (pH 7) -6.69
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 40489.4
Isoelectric Point (pI) 5.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 558 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017406 (462 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0483
Search term: hhqC
Search term: HhqC

Human Homologs

References

Functional genetic analysis reveals a 2-Alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria.
Diggle SP, Lumjiaktase P, Dipilato F, Winzer K, Kunakorn M, Barrett DA, Chhabra SR, Cámara M, Williams P
Chem Biol 2006 Jul;13(7):701-10
PubMed ID: 16873018