Burkholderia pseudomallei K96243, BPSS0243 (bhuS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0243
Name
bhuS
Replicon chromosome 2
Genomic location 329697 - 330848 (- strand)

Cross-References

RefSeq YP_110262.1
GI 53721277
Entrez 3095000
GI 53721277
INSDC CAH37689.1
NCBI Locus Tag BPSS0243
RefSeq YP_110262.1,GeneID
UniParc UPI000043B841
UniProtKB Acc Q63NQ7
UniProtKB ID Q63NQ7_BURPS
UniRef100 UniRef100_Q63NQ7
UniRef50 UniRef50_A3P229
UniRef90 UniRef90_A3P229

Product

Feature Type CDS
Coding Frame 1
Product Name
BhuS
Product Name Confidence: Class 2
Synonyms hemin ABC transport system-related protein
Evidence for Translation
Charge (pH 7) -0.38
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 41465.6
Isoelectric Point (pI) 6.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 95 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004243 (594 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0243
Search term: bhuS
Search term: BhuS

Human Homologs

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433