Burkholderia pseudomallei K96243, BPSS0170 (tssJ-3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0170
Name
tssJ-3
Replicon chromosome 2
Genomic location 228224 - 228736 (- strand)
CommentGene is part of a cluster known as the type VI secretion system gene cluster tss-3 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-4 cluster later (PMID:22007185)

Cross-References

RefSeq YP_110191.1
GI 53721206
Entrez 3096592
GI 53721206
INSDC CAH37615.1
NCBI Locus Tag BPSS0170
RefSeq YP_110191.1,GeneID
UniParc UPI000043B7FA
UniProtKB Acc Q63NX8
UniProtKB ID Q63NX8_BURPS
UniRef100 UniRef100_A0A069BDD9
UniRef50 UniRef50_A0A0B6RKQ8
UniRef90 UniRef90_A1UX21

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssJ-3 (T6SS-4)
Product Name Confidence: Class 2
Synonyms lipoprotein
Evidence for Translation
Charge (pH 7) 5.41
Kyte-Doolittle Hydrophobicity Value -0.175
Molecular Weight (kDa) 18451.0
Isoelectric Point (pI) 9.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG016121 (521 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0170
Search term: tssJ-3

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS.
Microbiology. 2007 Aug;153(Pt 8):2689-99.
PubMed ID: 17660433
PubMed ID: 22007185
Type VI secretion is a major virulence determinant in Burkholderia mallei.
Schell MA(1), Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, Mrázek J, Nierman WC, Deshazer D.
Mol Microbiol. 2007 Jun;64(6):1466-85.
PubMed ID: 17555434