Burkholderia pseudomallei K96243, BPSL3399 (atpH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3399
Name
atpH
Replicon chromosome 1
Genomic location 4038652 - 4039191 (- strand)

Cross-References

RefSeq YP_109992.1
GI 53721006
Entrez 3092138
GI 53721006
INSDC CAH37411.1
NCBI Locus Tag BPSL3399
RefSeq YP_109992.1,GeneID
UniParc UPI000043B733
UniProtKB Acc Q63PH7
UniProtKB ID ATPD_BURPS
UniRef100 UniRef100_Q3JXV5
UniRef50 UniRef50_Q8XU73
UniRef90 UniRef90_A3MQJ6

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP synthase F0F1 subunit delta
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (16.4 kDa, pI 5.17, PMID:21960737)
Charge (pH 7) -2.76
Kyte-Doolittle Hydrophobicity Value 0.239
Molecular Weight (kDa) 18986.7
Isoelectric Point (pI) 5.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 404 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000089 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3399
Search term: atpH

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP synthase peripheral stalk subunit OSCP [Source:HGNC Symbol;Acc:HGNC:850]
E-value: 7.5e-07
Percent Identity: 26.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268