Burkholderia pseudomallei K96243, BPSL3398 (atpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3398
Name
atpA
Replicon chromosome 1
Genomic location 4037064 - 4038605 (- strand)

Cross-References

RefSeq YP_109991.1
GI 53721005
Entrez 3092610
GI 53721005
INSDC CAH37410.1
NCBI Locus Tag BPSL3398
RefSeq YP_109991.1,GeneID
UniParc UPI000043B732
UniProtKB Acc Q63PH8
UniProtKB ID ATPA1_BURPS
UniRef100 UniRef100_A3P0Z2
UniRef50 UniRef50_Q2STE7
UniRef90 UniRef90_Q2STE7

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP synthase F0F1 subunit alpha
Synonyms
Evidence for Translation
Charge (pH 7) -6.86
Kyte-Doolittle Hydrophobicity Value -0.149
Molecular Weight (kDa) 55911.3
Isoelectric Point (pI) 5.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000090 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3398
Search term: atpA

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]
E-value: 4.9e-160
Percent Identity: 56.9
Ensembl 97, assembly GRCh38.p12
ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]
E-value: 4.9e-160
Percent Identity: 56.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268