Burkholderia pseudomallei K96243, BPSL3021 (ftsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3021
Name
ftsA
Replicon chromosome 1
Genomic location 3600467 - 3601699 (- strand)

Cross-References

RefSeq YP_109617.1
GI 53720631
Entrez 3093402
GI 53720631
INSDC CAH37033.1
NCBI Locus Tag BPSL3021
RefSeq YP_109617.1,GeneID
UniParc UPI000043B5C8
UniProtKB Acc Q63QK1
UniProtKB ID Q63QK1_BURPS
UniRef100 UniRef100_Q63QK1
UniRef50 UniRef50_A4G8T4
UniRef90 UniRef90_Q63QK1

Product

Feature Type CDS
Coding Frame 1
Product Name
cell division protein FtsA
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -13.86
Kyte-Doolittle Hydrophobicity Value 0.122
Molecular Weight (kDa) 43803.1
Isoelectric Point (pI) 4.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 486 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000452 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3021
Search term: ftsA

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268