Burkholderia pseudomallei K96243, BPSL2938 (leuS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2938
Name
leuS
Replicon chromosome 1
Genomic location 3508297 - 3510891 (- strand)

Cross-References

RefSeq YP_109532.1
GI 53720546
Entrez 3094550
GI 53720546
INSDC CAH36948.1
NCBI Locus Tag BPSL2938
RefSeq YP_109532.1,GeneID
UniParc UPI000043B575
UniProtKB Acc Q63QT6
UniProtKB ID SYL_BURPS
UniRef100 UniRef100_A3NZB6
UniRef50 UniRef50_Q087K2
UniRef90 UniRef90_Q2SZ91

Product

Feature Type CDS
Coding Frame 1
Product Name
leucyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -8.89
Kyte-Doolittle Hydrophobicity Value -0.249
Molecular Weight (kDa) 96150.2
Isoelectric Point (pI) 5.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000533 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2938
Search term: leuS

Human Homologs

Ensembl 97, assembly GRCh38.p12
leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]
E-value: 1.3e-149
Percent Identity: 36.9
Ensembl 97, assembly GRCh38.p12
leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]
E-value: 1.3e-149
Percent Identity: 36.9
Ensembl 97, assembly GRCh38.p12
leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095]
E-value: 1.3e-149
Percent Identity: 36.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268