Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSL2795
|
Name |
gmhA
Synonym: Sedoheptulose 7-phosphate isomerase |
Replicon | chromosome 1 |
Genomic location | 3342168 - 3342761 (- strand) |
RefSeq | YP_109390.1 |
GI | 53720404 |
Entrez | 3092932 |
GI | 53720404 |
NCBI Locus Tag | BPSL2795 |
RefSeq | YP_109390.1,GeneID |
UniProtKB Acc | Q93UJ2 |
UniProtKB ID | GMHA_BURPS |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
phosphoheptose isomerase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -3.17 |
Kyte-Doolittle Hydrophobicity Value | 0.077 |
Molecular Weight (kDa) | 20812.6 |
Isoelectric Point (pI) | 5.66 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5LU5 | ISOMERASE | 09/08/16 | A quantum half-site enzyme | BURKHOLDERIA PSEUDOMALLEI | 1.55 | X-RAY DIFFRACTION | 99.5 |
5LTZ | ISOMERASE | 09/07/16 | GmhA_mutant Q175E | BURKHOLDERIA PSEUDOMALLEI K96243 | 1.67 | X-RAY DIFFRACTION | 99.5 |
2X3Y | ISOMERASE | 01/28/10 | Crystal structure of GmhA from Burkholderia pseudomallei | BURKHOLDERIA PSEUDOMALLEI | 2.4 | X-RAY DIFFRACTION | 100.0 |
2XBL | ISOMERASE | 04/13/10 | Crystal structure of GmhA from Burkholderia pseudomallei in complex with product | BURKHOLDERIA PSEUDOMALLEI | 1.62 | X-RAY DIFFRACTION | 100.0 |
5LU7 | ISOMERASE | 09/08/16 | Heptose isomerase GmhA mutant - D61A | BURKHOLDERIA PSEUDOMALLEI K96243 | 1.92 | X-RAY DIFFRACTION | 99.5 |
5LU6 | ISOMERASE | 09/08/16 | Heptose isomerase mutant - H64Q | BURKHOLDERIA PSEUDOMALLEI | 1.67 | X-RAY DIFFRACTION | 99.5 |
Source 1 | |
Database | VFDB : VF0436 |
Category | Type I O-polysaccharide |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | |
Notes | |
Reference | 17984080 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 358 genera
|
Burkholderia Ortholog Group |
BG020186 (332 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSL2795
Search term: gmhA
Search term: phosphoheptose isomerase
|
A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei.
Kim MS, Shin DH
Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 Nov 1;65(Pt 11):1110-2
PubMed ID: 19923728
|
The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site.
Harmer NJ
J Mol Biol 2010 Jul 16;400(3):379-92
PubMed ID: 20447408
|