Burkholderia pseudomallei K96243, BPSL2666 (pgm)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2666
Name
pgm
Replicon chromosome 1
Genomic location 3189170 - 3190564 (- strand)

Cross-References

RefSeq YP_109262.1
GI 53720276
Entrez 3094110
GI 53720276
INSDC CAH36674.1
NCBI Locus Tag BPSL2666
RefSeq YP_109262.1,GeneID
UniParc UPI000043B48A
UniProtKB Acc Q63RK6
UniProtKB ID Q63RK6_BURPS
UniRef100 UniRef100_A3NYD6
UniRef50 UniRef50_C4KT45
UniRef90 UniRef90_C4KT45

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoglucomutase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (48.0 kDa, pI 5.00, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (47.5 kDa, pI 5.07, PMID:21960737)
Charge (pH 7) -9.63
Kyte-Doolittle Hydrophobicity Value -0.123
Molecular Weight (kDa) 50083.4
Isoelectric Point (pI) 5.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3UW2 ISOMERASE 11/30/11 X-ray Crystal Structure of Phosphoglucomutase/phosphomannomutase family protein (BTH_I1489)from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 1.95 X-RAY DIFFRACTION 97.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 657 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000749 (645 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2666
Search term: pgm

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268