Burkholderia pseudomallei K96243, BPSL2612 (zwf)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2612
Name
zwf
Replicon chromosome 1
Genomic location 3133594 - 3135063 (+ strand)

Cross-References

RefSeq YP_109208.1
GI 53720222
Entrez 3094730
GI 53720222
INSDC CAH36620.1
NCBI Locus Tag BPSL2612
RefSeq YP_109208.1,GeneID
UniParc UPI000043B454
UniProtKB Acc Q63RQ9
UniProtKB ID Q63RQ9_BURPS
UniRef100 UniRef100_A0A069BA51
UniRef50 UniRef50_Q0K136
UniRef90 UniRef90_A9AET5

Product

Feature Type CDS
Coding Frame 1
Product Name
glucose-6-phosphate 1-dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -3.18
Kyte-Doolittle Hydrophobicity Value -0.119
Molecular Weight (kDa) 54483.9
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 391 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000802 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2612
Search term: zwf

Human Homologs

Ensembl 97, assembly GRCh38.p12
glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057]
E-value: 1.9e-81
Percent Identity: 36.7
Ensembl 97, assembly GRCh38.p12
glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057]
E-value: 1.9e-81
Percent Identity: 36.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268