Burkholderia pseudomallei K96243, BPSL2522 (ompA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2522
Name
ompA
Replicon chromosome 1
Genomic location 3039644 - 3040318 (+ strand)

Cross-References

RefSeq YP_109118.1
GI 53720132
Entrez 3093812
GI 53720132
INSDC CAH36529.1
NCBI Locus Tag BPSL2522
RefSeq YP_109118.1,GeneID
UniParc UPI000043B3FA
UniProtKB Acc Q63RZ9
UniProtKB ID Q63RZ9_BURPS
UniRef100 UniRef100_C0LMZ9
UniRef50 UniRef50_A0A060NZ94
UniRef90 UniRef90_A4JCG8

Product

Feature Type CDS
Coding Frame 1
Product Name
outer membrane protein a
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (23.8 kDa, pI 4.29, PMID:21960737)
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 9.87
Kyte-Doolittle Hydrophobicity Value -0.286
Molecular Weight (kDa) 24077.4
Isoelectric Point (pI) 10.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 364 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000881 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2522
Search term: ompA

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268