Burkholderia pseudomallei K96243, BPSL2498

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2498
Name
Replicon chromosome 1
Genomic location 3010673 - 3012463 (- strand)

Cross-References

RefSeq YP_109093.1
GI 53720107
Entrez 3092451
GI 53720107
INSDC CAH36504.1
NCBI Locus Tag BPSL2498
RefSeq YP_109093.1,GeneID
UniParc UPI000043B3E2
UniProtKB Acc Q63S24
UniProtKB ID Q63S24_BURPS
UniRef100 UniRef100_A0A095JZF4
UniRef50 UniRef50_A1K8F6
UniRef90 UniRef90_I6AHH6

Product

Feature Type CDS
Coding Frame 1
Product Name
acyl-CoA dehydrogenase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -11.52
Kyte-Doolittle Hydrophobicity Value -0.047
Molecular Weight (kDa) 63654.0
Isoelectric Point (pI) 5.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 436 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005019 (1275 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2498

Human Homologs

Ensembl 97, assembly GRCh38.p12
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.7e-24
Percent Identity: 27.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268