Burkholderia pseudomallei K96243, BPSL2433

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2433
Name
Replicon chromosome 1
Genomic location 2939113 - 2940570 (- strand)

Cross-References

RefSeq YP_109025.1
GI 53720039
Entrez 3094614
GI 53720039
NCBI Locus Tag BPSL2433
RefSeq YP_109025.1,GeneID
UniProtKB Acc Q63S92
UniProtKB ID Q63S92_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidase
Synonyms
Evidence for Translation
Charge (pH 7) 2.26
Kyte-Doolittle Hydrophobicity Value -0.161
Molecular Weight (kDa) 50682.1
Isoelectric Point (pI) 9.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000971 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2433
Search term: peptidase

Human Homologs

Ensembl 97, assembly GRCh38.p12
HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476]
E-value: 5.3e-39
Percent Identity: 38.9
Ensembl 97, assembly GRCh38.p12
HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476]
E-value: 5.3e-39
Percent Identity: 38.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268