Burkholderia pseudomallei K96243, BPSL2433

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2433
Name
Replicon chromosome 1
Genomic location 2939113 - 2940570 (- strand)

Cross-References

RefSeq YP_109025.1
GI 53720039
Entrez 3094614
GI 53720039
NCBI Locus Tag BPSL2433
RefSeq YP_109025.1,GeneID
UniProtKB Acc Q63S92
UniProtKB ID Q63S92_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidase
Synonyms
Evidence for Translation
Charge (pH 7) 2.26
Kyte-Doolittle Hydrophobicity Value -0.161
Molecular Weight (kDa) 50682.1
Isoelectric Point (pI) 9.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Periplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000971 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2433
Search term: peptidase

Human Homologs

Ensembl 97, assembly GRCh38.p12
HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476]
E-value: 5.3e-39
Percent Identity: 38.9

Human Homologs

Ensembl 97, assembly GRCh38.p12
HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476]
E-value: 5.3e-39
Percent Identity: 38.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268