Burkholderia pseudomallei K96243, BPSL2422

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2422
Name
Replicon chromosome 1
Genomic location 2927947 - 2928504 (+ strand)

Cross-References

RefSeq YP_109014.1
GI 53720028
Entrez 3092950
GI 53720028
INSDC CAH36425.1
NCBI Locus Tag BPSL2422
RefSeq YP_109014.1,GeneID
UniParc UPI000043B395
UniProtKB Acc Q63SA2
UniProtKB ID EFP_BURPS
UniRef100 UniRef100_A3MM35
UniRef50 UniRef50_Q82W02
UniRef90 UniRef90_Q13VN6

Product

Feature Type CDS
Coding Frame 1
Product Name
elongation factor P
Synonyms
Evidence for Translation
Charge (pH 7) -7.07
Kyte-Doolittle Hydrophobicity Value -0.321
Molecular Weight (kDa) 20791.5
Isoelectric Point (pI) 4.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 592 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000982 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2422

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268