Burkholderia pseudomallei K96243, BPSL2403 (plcN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2403
Name
plcN
Replicon chromosome 1
Genomic location 2902870 - 2904972 (+ strand)

Cross-References

RefSeq YP_108995.1
GI 53720009
Entrez 3093316
GI 53720009
INSDC CAH36406.1
NCBI Locus Tag BPSL2403
RefSeq YP_108995.1,GeneID
UniParc UPI000043B382
UniProtKB Acc Q9RGS8
UniProtKB ID PHLN_BURPS
UniRef100 UniRef100_Q9RGS8
UniRef50 UniRef50_Q9RGS8
UniRef90 UniRef90_Q9RGS8

Product

Feature Type CDS
Coding Frame 1
Product Name
non-hemolytic phospholipase C
Synonyms
Evidence for Translation
Charge (pH 7) -2.57
Kyte-Doolittle Hydrophobicity Value -0.396
Molecular Weight (kDa) 77076.4
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 99 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001009 (1747 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2403
Search term: plcN

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268