Burkholderia pseudomallei K96243, BPSL2342 (hutU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2342
Name
hutU
Replicon chromosome 1
Genomic location 2830050 - 2831738 (- strand)

Cross-References

RefSeq YP_108938.1
GI 53719952
Entrez 3091781
GI 53719952
INSDC CAH36345.1
NCBI Locus Tag BPSL2342
RefSeq YP_108938.1,GeneID
UniParc UPI000043B349
UniProtKB Acc Q63SH8
UniProtKB ID Q63SH8_BURPS
UniRef100 UniRef100_A0A069B301
UniRef50 UniRef50_P25080
UniRef90 UniRef90_Q141F7

Product

Feature Type CDS
Coding Frame 1
Product Name
urocanate hydratase
Synonyms
Evidence for Translation
Charge (pH 7) -4.07
Kyte-Doolittle Hydrophobicity Value -0.264
Molecular Weight (kDa) 61555.5
Isoelectric Point (pI) 6.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 266 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002063 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2342
Search term: hutU

Human Homologs

Ensembl 97, assembly GRCh38.p12
urocanate hydratase 1 [Source:HGNC Symbol;Acc:HGNC:26444]
E-value: 1.2e-82
Percent Identity: 33.4

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268