Burkholderia pseudomallei K96243, BPSL2305

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2305
Name
Replicon chromosome 1
Genomic location 2778566 - 2780665 (+ strand)

Cross-References

RefSeq YP_108901.1
GI 53719915
Entrez 3093501
GI 53719915
INSDC CAH36308.1
NCBI Locus Tag BPSL2305
RefSeq YP_108901.1,GeneID
UniParc UPI000043B324
UniProtKB Acc Q63SL5
UniProtKB ID Q63SL5_BURPS
UniRef100 UniRef100_Q63SL5
UniRef50 UniRef50_G8PY41
UniRef90 UniRef90_A3NX56

Product

Feature Type CDS
Coding Frame 1
Product Name
oligopeptidase A
Synonyms
Evidence for Translation
Charge (pH 7) -22.19
Kyte-Doolittle Hydrophobicity Value -0.344
Molecular Weight (kDa) 77947.5
Isoelectric Point (pI) 4.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 335 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002034 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2305
Search term: oligopeptidase A

Human Homologs

Ensembl 97, assembly GRCh38.p12
neurolysin [Source:HGNC Symbol;Acc:HGNC:16058]
E-value: 6.8e-80
Percent Identity: 31.8

Human Homologs

Ensembl 97, assembly GRCh38.p12
neurolysin [Source:HGNC Symbol;Acc:HGNC:16058]
E-value: 6.8e-80
Percent Identity: 31.8

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268