Burkholderia pseudomallei K96243, BPSL2301 (aceE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2301
Name
aceE
Replicon chromosome 1
Genomic location 2770569 - 2773265 (- strand)

Cross-References

RefSeq YP_108897.1
GI 53719911
Entrez 3093625
GI 53719911
INSDC CAH36304.1
NCBI Locus Tag BPSL2301
RefSeq YP_108897.1,GeneID
UniParc UPI000043B320
UniProtKB Acc Q63SL9
UniProtKB ID Q63SL9_BURPS
UniRef100 UniRef100_A0A069B6P5
UniRef50 UniRef50_P0AFG9
UniRef90 UniRef90_A1V5N9

Product

Feature Type CDS
Coding Frame 1
Product Name
pyruvate dehydrogenase subunit E1
Synonyms
Evidence for Translation
Charge (pH 7) -16.81
Kyte-Doolittle Hydrophobicity Value -0.318
Molecular Weight (kDa) 100327.9
Isoelectric Point (pI) 5.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 372 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002030 (1227 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2301
Search term: aceE

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268