Burkholderia pseudomallei K96243, BPSL2299

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2299
Name
Replicon chromosome 1
Genomic location 2766719 - 2768488 (- strand)

Cross-References

RefSeq YP_108895.1
GI 53719909
Entrez 3091883
GI 53719909
INSDC CAH36302.1
NCBI Locus Tag BPSL2299
RefSeq YP_108895.1,GeneID
UniParc UPI000043B31E
UniProtKB Acc Q63SM1
UniProtKB ID Q63SM1_BURPS
UniRef100 UniRef100_A0A095MHD0
UniRef50 UniRef50_Q51225
UniRef90 UniRef90_A1V5N7

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -10.50
Kyte-Doolittle Hydrophobicity Value 0.018
Molecular Weight (kDa) 61635.6
Isoelectric Point (pI) 5.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 640 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002028 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2299

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 4.7e-90
Percent Identity: 41.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 4.7e-90
Percent Identity: 41.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268