Burkholderia pseudomallei K96243, BPSL2272 (pyrG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2272
Name
pyrG
Replicon chromosome 1
Genomic location 2735972 - 2737633 (- strand)

Cross-References

RefSeq YP_108868.1
GI 53719882
Entrez 3091437
GI 53719882
INSDC CAH36275.1
NCBI Locus Tag BPSL2272
RefSeq YP_108868.1,GeneID
UniParc UPI000043B303
UniProtKB Acc Q63SP8
UniProtKB ID PYRG_BURPS
UniRef100 UniRef100_A3ML79
UniRef50 UniRef50_P28595
UniRef90 UniRef90_Q13X05

Product

Feature Type CDS
Coding Frame 1
Product Name
CTP synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -7.33
Kyte-Doolittle Hydrophobicity Value -0.216
Molecular Weight (kDa) 61041.2
Isoelectric Point (pI) 6.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 655 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002002 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2272
Search term: pyrG
Search term: CTP synthetase

Human Homologs

Ensembl 97, assembly GRCh38.p12
CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520]
E-value: 5.9e-135
Percent Identity: 45.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520]
E-value: 5.9e-135
Percent Identity: 45.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520]
E-value: 5.9e-135
Percent Identity: 45.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268