Burkholderia pseudomallei K96243, BPSL2260

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2260
Name
Replicon chromosome 1
Genomic location 2725214 - 2726416 (- strand)

Cross-References

RefSeq YP_108856.1
GI 53719870
Entrez 3093616
GI 53719870
INSDC CAH36263.1
NCBI Locus Tag BPSL2260
RefSeq YP_108856.1,GeneID
UniParc UPI000043B2F7
UniProtKB Acc Q63SR0
UniProtKB ID Q63SR0_BURPS
UniRef100 UniRef100_Q3JQR6
UniRef50 UniRef50_Q3JQR6
UniRef90 UniRef90_Q3JQR6

Product

Feature Type CDS
Coding Frame 1
Product Name
tryptophanyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -6.55
Kyte-Doolittle Hydrophobicity Value -0.478
Molecular Weight (kDa) 45447.6
Isoelectric Point (pI) 5.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 635 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001990 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2260

Human Homologs

Ensembl 97, assembly GRCh38.p12
tryptophanyl tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:12730]
E-value: 1.3e-35
Percent Identity: 41.8

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268