Burkholderia pseudomallei K96243, BPSL2257

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2257
Name
Replicon chromosome 1
Genomic location 2722400 - 2723542 (- strand)

Cross-References

RefSeq YP_108853.1
GI 53719867
Entrez 3092580
GI 53719867
INSDC CAH36260.1
NCBI Locus Tag BPSL2257
RefSeq YP_108853.1,GeneID
UniParc UPI000043B2F4
UniProtKB Acc Q63SR3
UniProtKB ID Q63SR3_BURPS
UniRef100 UniRef100_A0A069B2F9
UniRef50 UniRef50_A9AHL5
UniRef90 UniRef90_Q2SXB2

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein
Synonyms
Evidence for Translation
Charge (pH 7) -1.06
Kyte-Doolittle Hydrophobicity Value -0.363
Molecular Weight (kDa) 41189.8
Isoelectric Point (pI) 6.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 63 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001987 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2257
Search term: lipoprotein

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268