Burkholderia pseudomallei K96243, BPSL2237 (batA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2237
Name
batA
Replicon chromosome 1
Genomic location 2696054 - 2697886 (- strand)

Cross-References

RefSeq YP_108832.1
GI 53719846
Entrez 3092820
GI 53719846
INSDC CAH36239.1
NCBI Locus Tag BPSL2237
RefSeq YP_108832.1,GeneID
UniParc UPI000043B2DF
UniProtKB Acc Q63ST4
UniProtKB ID Q63ST4_BURPS
UniRef100 UniRef100_Q63ST4
UniRef50 UniRef50_Q3JQU3
UniRef90 UniRef90_Q3JQU3

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia autotransporter A, BatA
Product Name Confidence: Class 1
Synonyms exported lipase
Evidence for Translation
Charge (pH 7) 10.10
Kyte-Doolittle Hydrophobicity Value 0.013
Molecular Weight (kDa) 64289.1
Isoelectric Point (pI) 9.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019895 (316 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2237
Search term: batA

Human Homologs

References

Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replication and a novel protein conferring serum resistance.
Lazar Adler NR, Stevens MP, Dean RE, Saint RJ, Pankhania D, Prior JL, Atkins TP, Kessler B, Nithichanon A, Lertmemongkolchai G, Galyov EE
PLoS One 2015;10(4):e0121271
PubMed ID: 25830295