Burkholderia pseudomallei K96243, BPSL2203

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2203
Name
Replicon chromosome 1
Genomic location 2645029 - 2646981 (- strand)

Cross-References

RefSeq YP_108798.1
GI 53719812
Entrez 3092317
GI 53719812
INSDC CAH36205.1
NCBI Locus Tag BPSL2203
RefSeq YP_108798.1,GeneID
UniParc UPI000043B2BD
UniProtKB Acc Q63SW8
UniProtKB ID Q63SW8_BURPS
UniRef100 UniRef100_A0A095M9F9
UniRef50 UniRef50_Q1LLF1
UniRef90 UniRef90_Q2SX42

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter substrate-binding protein
Synonyms
Evidence for Translation
Charge (pH 7) 17.17
Kyte-Doolittle Hydrophobicity Value -0.223
Molecular Weight (kDa) 71682.5
Isoelectric Point (pI) 9.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 426 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001951 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2203

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268